SCHEMBL16175459

SCHEMBL16175459

OCc1c(F)ccc(-c2cccc3nc(-c4occ5ccccc45)cn23)c1F

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16175458 0.84 NR4A2 (0.39) NR4A2
SCHEMBL3432026 0.81 NR4A2 (0.63) NR4A2
SCHEMBL16175457 0.77 CCNE2 (0.31) NR4A2
SCHEMBL3431476 0.74 NR4A2 (0.48) NR4A2
SCHEMBL3432023 0.69 NR4A2 (0.39) NR4A2
SCHEMBL3432021 0.65 NR4A2 (0.63) NR4A2
SCHEMBL3431473 0.62 ADORA2A (0.32)
SCHEMBL2064734 0.60 NR4A2 (0.73) NR4A2
SCHEMBL217543 0.60 ADORA2A (0.42) NR4A2
SCHEMBL3428638 0.60 NR4A2 (0.68) NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262805-B1 POLYSUBSTITUTED DERIVATIVES OF 2-HETEROARYL-6-PHENYL-IMIDAZO[L,2-A] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF SANOFI SA (FR) 2014-10-22 EP claimed