Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.68 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16175621 | 0.88 | BACE1 (0.61) | BACE1BACE2CYP2D6 | |
| SCHEMBL15703841 | 0.85 | BACE1 (0.69) | BACE1BACE2 | |
| SCHEMBL1978890 | 0.85 | BACE1 (0.69) | BACE1BACE2CYP2D6 | |
| SCHEMBL1978473 | 0.83 | BACE1 (0.66) | BACE1BACE2CYP2D6 | |
| SCHEMBL1978476 | 0.83 | BACE1 (0.66) | BACE1BACE2CYP2D6 | |
| SCHEMBL1981201 | 0.82 | BACE1 (0.65) | BACE1BACE2CYP2D6 | |
| SCHEMBL1981199 | 0.82 | BACE1 (0.65) | BACE1BACE2CYP2D6 | |
| SCHEMBL1981197 | 0.82 | BACE1 (0.65) | BACE1BACE2CYP2D6 | |
| SCHEMBL1977118 | 0.82 | BACE1 (0.65) | BACE1BACE2CYP2D6 | |
| SCHEMBL1976469 | 0.82 | BACE1 (0.84) | BACE1BACE2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509966-B1 | AMINO OXAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2014-10-22 | — | — | EP | claimed |