SCHEMBL16178254

SCHEMBL16178254

C/C=C\[C](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20215 1.00
SCHEMBL23869 1.00
SCHEMBL9317865 0.96
SCHEMBL2169129 0.75
SCHEMBL6860057 0.75
SCHEMBL19423950 0.73
SCHEMBL10445447 0.70
SCHEMBL6544685 0.70
SCHEMBL790714 0.70
SCHEMBL735415 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12012467-B2 Small molecule DCN1 inhibitors and therapeutic methods using the same REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-06-18 US disclosed
CN-110740996-B Covalent small molecule DCN1 inhibitors and methods of treatment using the same 密执安大学评议会 2024-01-09 CN disclosed
EP-3609876-B1 COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME UNIV MICHIGAN REGENTS (US) 2022-03-30 EP disclosed
CN-113292923-A Silicone gel with reduced gas emissions 艾伦塔斯有限公司 2021-08-24 CN disclosed
US-20200109167-A1 SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME UNIV MICHIGAN REGENTS (US) 2020-04-09 US disclosed
EP-3609876-A1 COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME The Regents of The University of Michigan (US) 2020-02-19 EP disclosed
EP-3601245-A1 SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME The Regents of The University of Michigan (US) 2020-02-05 EP disclosed
CN-110740996-A Covalent small molecule DCN1 inhibitors and methods of treatment using the same 密执安大学评议会 2020-01-31 CN disclosed
WO-2018191199-A1 COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2018-10-18 WO disclosed
US-20180289677-A1 Covalent Small Molecule DCN1 Inhibitors and Therapeutic Methods Using the Same THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2018-10-11 US disclosed
WO-2018183411-A1 SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2018-10-04 WO disclosed
US-9944824-B2 Gas-emission-reduced silicone gel ELANTAS GMBH (DE) 2018-04-17 US disclosed
US-20170327713-A1 ONE-COMPONENT, CURABLE SILICONE COMPOSITION THAT IS STABLE IN STORAGE ELANTAS GMBH (DE) 2017-11-16 US disclosed
US-9765236-B2 One-component, solvent-free organosiloxane composition for application to printed circuit boards by means of a cross-cut nozzle ELANTAS GMBH (DE) 2017-09-19 US disclosed
EP-3036297-B1 GAS-EMISSION-REDUCED SILICONE GEL ELANTAS GMBH (DE) 2017-04-19 EP disclosed
US-20160200940-A1 GAS-EMISSION-REDUCED SILICONE GEL ELANTAS GMBH (DE) 2016-07-14 US disclosed
US-20140315032-A1 ONE-COMPONENT, SOLVENT-FREE ORGANOSILOXANE COMPOSITION FOR APPLICATION TO PRINTED CIRCUIT BOARDS BY MEANS OF A CROSS-CUT NOZZLE ELANTAS GMBH (DE) 2014-10-23 US disclosed