Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.61 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.60 |
| ▸ | OSBP | P22059 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.51 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.49 |
| ▸ | UGCG | Q16739 | 2/20 | 0.49 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495767 | 1.00 | POLA1 (0.61) | POLA1CYP46A1OSBPUSP2LMNA | |
| SCHEMBL10360417 | 1.00 | POLA1 (0.61) | POLA1CYP46A1OSBPUSP2LMNA | |
| SCHEMBL10495770 | 1.00 | POLA1 (0.61) | POLA1CYP46A1OSBPUSP2LMNA | |
| SCHEMBL10360419 | 1.00 | POLA1 (0.61) | POLA1CYP46A1OSBPUSP2LMNA | |
| SCHEMBL12065992 | 0.95 | POLA1 (0.59) | POLA1CYP46A1OSBPUSP2LMNA | |
| SCHEMBL9978604 | 0.95 | POLA1 (0.59) | POLA1CYP46A1OSBPUSP2LMNA | |
| SCHEMBL20060713 | 0.95 | POLA1 (0.59) | POLA1CYP46A1OSBPUSP2LMNA | |
| SCHEMBL9978606 | 0.95 | POLA1 (0.59) | POLA1CYP46A1OSBPUSP2LMNA | |
| SCHEMBL11214131 | 0.94 | OSBP (0.57) | POLA1CYP46A1OSBPUSP2LMNA | |
| SCHEMBL2831166 | 0.92 | DPP4 (0.61) | POLA1CYP46A1OSBPUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9974727-B2 | Hair growth and hair restoration material | INSTITUTE OF RHEOLOGICAL FUNCTION OF FOOD CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |
| US-20160184207-A1 | HAIR GROWTH AND HAIR RESTORATION MATERIAL | INST OF RHEOLOGICAL FUNCTION OF FOOD CO LTD (JP) | 2016-06-30 | — | — | US | disclosed |
| US-20140316120-A1 | HAIR GROWTH AND HAIR RESTORATION MATERIAL | INSTITUTE OF RHEOLOGICAL FUNCTION OF FOOD CO., LTD. (JP) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184207-A1 | HAIR GROWTH AND HAIR RESTORATION MATERIAL | CYP17A1, CYP46A1, CYP21A2 | POLA1 878/4885CYP46A1 2/4885OSBP 157/4885 |
| US-20140316120-A1 | HAIR GROWTH AND HAIR RESTORATION MATERIAL | CYP17A1, CYP46A1, CYP21A2 | POLA1 1262/4885CYP46A1 2/4885OSBP 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.