Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952847 | 0.90 | KMT2A (0.45) | KMT2AGLSCA1CA2CA7 | |
| SCHEMBL21952754 | 0.90 | KMT2A (0.45) | KMT2AGLSCA1CA2CA7 | |
| SCHEMBL17906508 | 0.88 | CA1 (0.43) | KMT2AGLSCA1CA2CA7 | |
| SCHEMBL17906506 | 0.84 | CA1 (0.42) | KMT2AGLSCA1CA2CA7 | |
| SCHEMBL16554064 | 0.84 | CA1 (0.44) | KMT2AGLSCA1CA2CA7 | |
| SCHEMBL16554062 | 0.84 | CA1 (0.44) | KMT2AGLSCA1CA2CA7 | |
| SCHEMBL16554061 | 0.84 | CA1 (0.44) | KMT2AGLSCA1CA2CA7 | |
| SCHEMBL17906505 | 0.84 | CA1 (0.44) | KMT2AGLSCA1CA2CA7 | |
| SCHEMBL19813666 | 0.83 | KMT2A (0.44) | KMT2AGLSCA1CA2CA7 | |
| SCHEMBL19813668 | 0.83 | KMT2A (0.44) | KMT2AGLSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379540-B1 | DIPEPTOID PRODRUGS AND THE USE THEREOF | BAYER IP GMBH (DE) | 2014-10-22 | — | — | EP | disclosed |