SCHEMBL16185474

SCHEMBL16185474

c1ccc(-c2cc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)nc(-c3ccc(-c4ccc5oc6ccccc6c5c4)cc3)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.40
MEN1 O00255 6/20 0.40
KMT2A Q03164 6/20 0.40
ALDH1A1 P00352 6/20 0.40
HPGD P15428 6/20 0.40
NTSR1 P30989 1/20 0.40
PLA2G2A P14555 3/20 0.39
PLA2G4A P47712 3/20 0.39
KDM4E B2RXH2 5/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
ATM Q13315 1/20 0.39
CHEK2 O96017 1/20 0.38
LMNA P02545 2/20 0.36
GLA P06280 1/20 0.36
PLA2G10 O15496 1/20 0.35
MAPK1 P28482 2/20 0.35
PTPN1 P18031 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9881127 1.00 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185525 1.00 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185423 1.00 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185420 1.00 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16805645 0.98 MAPT (0.38) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185618 0.98 CHEK2 (0.39) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185570 0.98 CHEK2 (0.39) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185614 0.97 MEN1 (0.39) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL19276016 0.97 MEN1 (0.39) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL11998291 0.97 MAPT (0.39) MAPTMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9847501-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2017-12-19 US disclosed
US-9847501-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2017-12-19 US disclosed
US-20140312338-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed
US-20140312338-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed