SCHEMBL16185692

SCHEMBL16185692

c1ccc(-c2cc(-c3ccc(-c4ccc5c(c4)oc4ccccc45)cc3)nc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.40
MEN1 O00255 7/20 0.40
KMT2A Q03164 7/20 0.40
ALDH1A1 P00352 6/20 0.40
HPGD P15428 6/20 0.40
NTSR1 P30989 1/20 0.40
KDM4E B2RXH2 5/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 2/20 0.39
MMP12 P39900 1/20 0.37
MMP13 P45452 1/20 0.37
LMNA P02545 2/20 0.36
GLA P06280 1/20 0.36
HCRTR1 O43613 1/20 0.36
PTGER4 P35408 1/20 0.35
MAPK1 P28482 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
AHR P35869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16185393 1.00 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185717 1.00 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL17899172 0.98 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16811398 0.98 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL19397649 0.98 KDM4E (0.41) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16805636 0.97 MAPT (0.37) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185398 0.96 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL17899165 0.96 MAPT (0.40) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185678 0.96 KDM4E (0.41) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL16185714 0.95 MAPT (0.38) MAPTMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9847501-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2017-12-19 US disclosed
US-9847501-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2017-12-19 US disclosed
US-20140312338-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed
US-20140312338-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed