Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.74 |
| ▸ | BLK | P51451 | 14/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | TEC | P42680 | 1/20 | 0.53 |
| ▸ | TXK | P42681 | 1/20 | 0.53 |
| ▸ | BMX | P51813 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15998159 | 0.85 | BTK (1.00) | BTKBLKEGFRERBB2TEC | |
| SCHEMBL2948801 | 0.83 | BTK (0.77) | BTKBLKLCKKITKDR | |
| SCHEMBL15998149 | 0.80 | BTK (1.00) | BTKBLKLCK | |
| SCHEMBL2951053 | 0.77 | LCK (0.82) | BTKBLKJAK3LCKKDR | |
| SCHEMBL14611027 | 0.74 | LCK (0.64) | BTKBLKLCKKDRMAPK14 | |
| SCHEMBL16188453 | 0.74 | BTK (0.82) | BTKBLKEGFRERBB2TEC | |
| SCHEMBL6228429 | 0.73 | NPC1 (0.70) | — | |
| SCHEMBL16188450 | 0.72 | BTK (0.82) | BTKBLKEGFRERBB2TEC | |
| SCHEMBL15998135 | 0.71 | BTK (0.81) | BTKBLKEGFRERBB2TEC | |
| SCHEMBL15998171 | 0.71 | BTK (1.00) | BTKBLKEGFRERBB2TEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014169710-A1 | KINASE INHIBITOR AND METHOD FOR TREATING RELATED DISEASES | 北京大学深圳研究生院 (CN) | 2014-10-23 | — | — | WO | disclosed |