Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.49 |
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16189976 | 0.94 | F10 (0.47) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL16189986 | 0.93 | F10 (0.51) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL16190043 | 0.86 | F10 (0.58) | F10F2SLC29A1 | |
| SCHEMBL16189973 | 0.86 | F10 (0.65) | F10F2SLC29A1 | |
| SCHEMBL16189988 | 0.86 | F10 (0.47) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL16189967 | 0.85 | F10 (0.48) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL28844061 | 0.85 | F10 (0.56) | F10F2SLC29A1 | |
| SCHEMBL15628281 | 0.85 | F10 (0.66) | F10F2SLC29A1 | |
| SCHEMBL16189956 | 0.84 | F10 (0.54) | F10F2SLC29A1 | |
| SCHEMBL16189966 | 0.84 | F10 (0.51) | F10F2SLC29A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026392-B | 4,5-dihydro-pyrazolo [3, 4-c] pyrid-2-ones, preparation method and application thereof | 四川海思科制药有限公司 | 2017-05-10 | — | — | CN | disclosed |
| WO-2014169845-A2 | 4,5-DIHYDRO-PYRAZOLO [3, 4-C] PYRID-2-ONES, PREPARATION METHOD AND APPLICATION THEREOF | 四川海思科制药有限公司 (CN) | 2014-10-23 | — | — | WO | disclosed |
| CN-104109165-A | 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-one derivatives, and preparation method and application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2014-10-22 | — | — | CN | disclosed |