SCHEMBL161918

SCHEMBL161918

CN(C)c1ncccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30863955 0.97 HSD17B10 (0.44)
SCHEMBL6350251 0.73
SCHEMBL30778143 0.73
SCHEMBL4720221 0.73
SCHEMBL18226066 0.73
SCHEMBL23351695 0.73
Hydrochloric Acid SCHEMBL28946229 0.71 HSD17B10 (0.40)
SCHEMBL358354 0.71
Hydrochloric Acid SCHEMBL20515791 0.71 KMT2A (0.40)
SCHEMBL3129653 0.71 HSD17B10 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120019822-A CD44v 6-targeted radioactive drug and preparation method and application thereof 复旦大学附属肿瘤医院 2025-05-20 CN claimed
CN-113881026-B High-fluidity liquid crystal polymer and film thereof 宁波聚嘉新材料科技有限公司 2022-12-06 CN claimed
WO-2022208382-A1 NOVEL DIALKOXYNAPHTHO[2,3-C]FURAN-1(3H)-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE OR SARS-COV-2 INFECTION DISEASE, COMPRISING SAME 동화약품주식회사 2022-10-06 WO claimed
CN-114144230-A Macrocyclic azolopyridine derivatives as EED and PRC2 modulators 弗尔康医疗公司 2022-03-04 CN claimed
CN-113881026-A High-fluidity liquid crystal polymer and film thereof 宁波聚嘉新材料科技有限公司 2022-01-04 CN claimed
CN-110467176-B Functionalized carbon nanotube composite material, preparation method thereof and polarizing device 许昌学院 2020-10-02 CN claimed
US-10772874-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. 2020-09-15 US claimed
CN-110467176-A A kind of functionalized carbon nano-tube composite material, preparation method and polarizer UNIV XUCHANG 2019-11-19 CN claimed
US-10456382-B2 Compounds and compositions for the inhibition of NAMPT FORMA TM, LLC (US) 2019-10-29 US claimed
US-20190105307-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT Valo Health, LLC 2019-04-11 US claimed
WO-2012031197-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT FORMA THERAPEUTICS, INC. (US) 2012-03-08 WO claimed
CN-101914065-A Help to treat pyrimidine derivatives by the disease of CRTH2 mediation ACTIMIS PHARMACEUTICALS INC 2010-12-15 CN claimed
CN-101506201-A Novel heteroaryl substituted benzoxazoles ASTRAZENECA AB (SE) 2009-08-12 CN claimed
CN-1960726-A Composition comprising a jnk inhibitor and cyclosporin APPLIED RESEARCH SYSTEMS (AN) 2007-05-09 CN claimed
CN-1922170-A Novel hydroxy-6-heteroarylphenanthridines and their use as PDE4 ALTANA PHARMA AG (DE) 2007-02-28 CN claimed
CN-1296346-C Acylated 6,7,8,9-tetrahydro-5H-benzocycloheptenyl amines and their use as pharmaceutical SANOFI AVENTIS DEUTSCHLAND (DE) 2007-01-24 CN claimed
CN-1809539-A Pyrimidine derivatives useful in the treatment of diseases mediated by CRTH2 ACTIMIS PHARMACEUTICALS INC (US) 2006-07-26 CN claimed
CN-1759095-A N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives ELAN PHARM INC (US) 2006-04-12 CN claimed
CN-1264377-A Substituted pyrazoles as P38 kinase inhabitors SEARLE & CO (US) 2000-08-23 CN claimed
US-4212937-A NITROGEN-CONTAINING HETEROCYCLIC BASE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-15 US claimed