⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343615 | 0.82 | — | — | |
| SCHEMBL3340436 | 0.79 | — | — | |
| SCHEMBL3340432 | 0.79 | — | — | |
| SCHEMBL1747873 | 0.76 | CHRM3 (0.31) | — | |
| SCHEMBL1292180 | 0.75 | — | — | |
| SCHEMBL12465180 | 0.72 | — | — | |
| SCHEMBL7541983 | 0.70 | KMT2A (0.36) | — | |
| SCHEMBL15233748 | 0.67 | CHRM3 (0.31) | — | |
| SCHEMBL12949141 | 0.65 | CHRM3 (0.37) | — | |
| SCHEMBL12928650 | 0.64 | CHRM3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10287281-B2 | Pyrazoline derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-14 | — | — | US | disclosed |
| EP-2748155-B1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| US-20170283405-A1 | PYRAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-05 | — | — | US | disclosed |
| US-9776994-B2 | Pyrazoline derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-03 | — | — | US | disclosed |
| WO-2014172871-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | WO | disclosed |