Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197618 | 0.98 | POLB (0.67) | POLBTDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL14697021 | 0.85 | KMT2A (0.72) | POLBTDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL12793844 | 0.84 | TDP1 (0.72) | POLBTDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL12793858 | 0.83 | TDP1 (0.69) | POLBTDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL14696866 | 0.82 | SMN1; SMN2 (0.74) | POLBALDH1A1LMNAHTTKMT2A | |
| SCHEMBL2744997 | 0.82 | USP2 (0.69) | POLBTDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL16197383 | 0.82 | POLB (0.84) | POLBTDP1ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9194904 | 0.81 | POLB (0.61) | POLBTDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL14697004 | 0.81 | SMN1; SMN2 (0.72) | ALDH1A1LMNAHTTKMT2AMAPT | |
| SCHEMBL19334304 | 0.81 | USP5 (0.79) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014173904-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY | VIB VZW (BE) | 2014-10-30 | — | — | WO | disclosed |
| WO-2014173904-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY | VIB VZW (BE) | 2014-10-30 | — | — | WO | disclosed |