Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 6/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 6/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24420265 | 1.00 | FGFR1 (0.48) | FGFR1SLC22A6LMNATSHRHTT | |
| SCHEMBL24420129 | 1.00 | FGFR1 (0.48) | FGFR1SLC22A6LMNATSHRHTT | |
| SCHEMBL10049650 | 0.86 | FGFR1 (0.56) | FGFR1SLC22A6LMNAEP300THRB | |
| SCHEMBL14948806 | 0.86 | FGFR1 (0.56) | FGFR1SLC22A6LMNAEP300THRB | |
| SCHEMBL12652844 | 0.85 | FGFR1 (0.51) | FGFR1SLC22A6LMNAEP300THRB | |
| SCHEMBL14478248 | 0.83 | FGFR1 (0.50) | FGFR1SLC22A6 | |
| SCHEMBL24420125 | 0.83 | FGFR1 (0.45) | FGFR1SLC22A6LMNAEP300THRB | |
| SCHEMBL27054002 | 0.83 | FGFR1 (0.45) | FGFR1SLC22A6LMNAEP300MCHR1 | |
| SCHEMBL12950562 | 0.83 | FGFR1 (0.45) | FGFR1SLC22A6LMNAEP300THRB | |
| SCHEMBL27058263 | 0.83 | FGFR1 (0.45) | FGFR1SLC22A6LMNAEP300MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |
| WO-2014175974-A2 | ARTIFICIAL NUCLEIC ACIDS | ELITECH HOLDING B.V. (NL) | 2014-10-30 | — | — | WO | disclosed |