Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16199041 | 1.00 | GSK3A (0.38) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL9977821 | 0.83 | GSK3A (0.43) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL16199389 | 0.83 | GSK3A (0.43) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL16199026 | 0.83 | GSK3A (0.43) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL16199040 | 0.83 | GSK3A (0.43) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL16199390 | 0.83 | GSK3A (0.43) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL16199042 | 0.83 | GSK3A (0.51) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL16199059 | 0.83 | GSK3A (0.51) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL9970867 | 0.75 | GSK3A (0.35) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL16199058 | 0.75 | GSK3A (0.43) | GSK3AGSK3BJAK2SRCFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871774-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-10-28 | — | — | US | disclosed |