Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16199071 | 0.99 | CCNT1 (0.38) | CCNT1CDK4CCNA2CCND1CDK2 | |
| SCHEMBL16199112 | 0.99 | CCNT1 (0.38) | CCNT1CDK4CCNA2CCND1CDK2 | |
| SCHEMBL16199050 | 0.91 | CCNT1 (0.35) | CCNT1CDK4CCNA2CCND1CDK2 | |
| SCHEMBL16199114 | 0.91 | CCNT1 (0.35) | CCNT1CDK4CCNA2CCND1CDK2 | |
| SCHEMBL16199113 | 0.89 | CNR1 (0.38) | CCNT1CDK4CCNA2CCND1CDK2 | |
| SCHEMBL16199102 | 0.88 | — | — | |
| SCHEMBL16199047 | 0.88 | — | — | |
| SCHEMBL16199101 | 0.87 | CCNT1 (0.38) | CCNT1CDK4CCNA2CCND1CDK2 | |
| SCHEMBL16199044 | 0.87 | CCNT1 (0.38) | CCNT1CDK4CCNA2CCND1CDK2 | |
| SCHEMBL15400455 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871774-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-10-28 | — | — | US | disclosed |