Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863034 | 0.91 | KCNH2 (0.49) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862723 | 0.85 | NR1I2 (0.49) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL863082 | 0.84 | KCNH2 (0.49) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862819 | 0.82 | KCNH2 (0.47) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL863159 | 0.82 | KCNH2 (0.49) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL863009 | 0.82 | KCNH2 (0.49) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862641 | 0.79 | KCNH2 (0.50) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862991 | 0.78 | KCNH2 (0.51) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862678 | 0.78 | KCNH2 (0.51) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862925 | 0.77 | NR1I2 (0.49) | NR1I2KCNH2SCN9ACYP3A4SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396329-B1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2014-10-29 | — | — | EP | disclosed |