Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ACACB | O00763 | 2/20 | 0.56 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | ACACA | Q13085 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12243191 | 0.91 | S1PR1 (0.59) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2350982 | 0.91 | RARB (0.70) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12294471 | 0.89 | S1PR1 (0.58) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13926721 | 0.89 | S1PR1 (0.69) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7340382 | 0.88 | S1PR1 (0.57) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12243347 | 0.87 | S1PR1 (0.56) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12243096 | 0.86 | S1PR1 (0.59) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12270837 | 0.85 | S1PR1 (0.64) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15338399 | 0.83 | RARB (0.77) | RARBTP53TSHRPLA2G4BPTPN11 | |
| SCHEMBL35210439 | 0.82 | S1PR1 (0.67) | S1PR1S1PR3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350119-B1 | LIPOPEPTIDE COMPOUNDS AND THEIR USE | UNIQUEST PTY LTD (AU) | 2014-10-29 | — | — | EP | disclosed |