Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904556 | 0.80 | PIK3CD (0.43) | USP30PARP1PIK3CDHDAC4HDAC6 | |
| SCHEMBL9904557 | 0.80 | PIK3CD (0.43) | USP30PARP1PIK3CDHDAC4HDAC6 | |
| SCHEMBL9904659 | 0.78 | PIM1 (0.53) | USP30PARP1PIK3CDHDAC4HDAC6 | |
| SCHEMBL9904658 | 0.78 | PIM1 (0.53) | USP30PARP1PIK3CDHDAC4HDAC6 | |
| SCHEMBL9904399 | 0.73 | TYK2 (0.62) | PIK3CDCHEK2PIM1PIM2PIK3CA | |
| SCHEMBL9904397 | 0.73 | TYK2 (0.62) | PIK3CDCHEK2PIM1PIM2PIK3CA | |
| SCHEMBL9905828 | 0.70 | TYK2 (0.58) | PIK3CDCHEK2PIM1PIM2TYK2 | |
| SCHEMBL9904423 | 0.70 | TYK2 (0.58) | PIK3CDCHEK2PIM1PIM2TYK2 | |
| SCHEMBL9904239 | 0.69 | PIM1 (0.43) | USP30PARP1HDAC4HDAC6PIM1 | |
| SCHEMBL29414084 | 0.66 | CDK2 (0.47) | USP30PARP1JAK1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796456-A1 | Bicyclic compounds as Pim inhibitors | Amgen Inc. (US) | 2014-10-29 | — | — | EP | disclosed |