SCHEMBL16200738

SCHEMBL16200738

Cc1ccc(C(C)C(=O)c2ccc(OC(C)C)c(OC(C)C)c2OC(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.40
MAPT P10636 4/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
PPARG P37231 1/20 0.38
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38
IRAK4 Q9NWZ3 2/20 0.36
ALDH1A1 P00352 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
GAA P10253 1/20 0.33
NLRP1 Q9C000 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18800174 0.89 CYP3A4 (0.47) HIF1AMAPTKMT2AMEN1CYP3A4
SCHEMBL18800177 0.82 MAPT (0.50) HIF1AMAPTKMT2AMEN1CYP3A4
SCHEMBL19543406 0.80 IRAK4 (0.42) MAPTKMT2AMEN1IDO1TDO2
SCHEMBL16200739 0.78 KMT2A (0.45) HIF1AMAPTKMT2AMEN1CYP3A4
SCHEMBL16200747 0.78 KMT2A (0.45) HIF1AMAPTKMT2AMEN1CYP3A4
SCHEMBL16200746 0.74 MAPT (0.50) HIF1AMAPTKMT2AMEN1CYP3A4
SCHEMBL4351258 0.72 IRAK4 (0.41) MAPTKMT2AIDO1TDO2IRAK4
SCHEMBL11969532 0.72 IRAK4 (0.41) MAPTKMT2AIDO1TDO2IRAK4
SCHEMBL20445406 0.71 IRAK4 (0.40) PPARGIDO1TDO2IRAK4ALDH1A1
SCHEMBL29066949 0.70 KMT2A (0.44) MAPTKMT2AMEN1CYP3A4PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9642249-B2 Resin composition, prepreg, and substrate employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-05-02 US disclosed
US-9012572-B2 Polyphenylene ether oligomer and article employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-04-21 US disclosed
US-20140322545-A1 RESIN COMPOSITION, PREPREG, AND SUBSTRATE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-10-30 US disclosed
US-20140323666-A1 POLYPHENYLENE ETHER OLIGOMER AND ARTICLE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-10-30 US disclosed