SCHEMBL16201606

SCHEMBL16201606

COc1ccc(C(C)C(=O)c2ccc(O)c(OC)c2OC)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
MAPT P10636 3/20 0.68
CYP3A4 P08684 2/20 0.68
PPARG P37231 1/20 0.68
HIF1A Q16665 3/20 0.44
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
PTGS2 P35354 3/20 0.41
PTGS1 P23219 2/20 0.41
AKR1C3 P42330 2/20 0.41
AKR1C2 P52895 2/20 0.41
TSHR P16473 2/20 0.41
CDC42 P60953 1/20 0.41
RAC1 P63000 1/20 0.41
CYP1A2 P05177 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16201700 0.84 MAPT (0.59) MEN1KMT2AMAPTCYP3A4PPARG
SCHEMBL16201608 0.81 MAPT (0.59) MEN1KMT2AMAPTCYP3A4PPARG
Angolensin (R) SCHEMBL2544863 0.81 CYP3A4 (1.00) MEN1KMT2AMAPTCYP3A4PPARG
Angolensin (R) SCHEMBL12998482 0.81 CYP3A4 (1.00) MEN1KMT2AMAPTCYP3A4PPARG
Angolensin (R) SCHEMBL30591540 0.81 CYP3A4 (1.00) MEN1KMT2AMAPTCYP3A4PPARG
SCHEMBL13090328 0.80 CYP3A4 (0.74) MEN1KMT2AMAPTCYP3A4PPARG
SCHEMBL16200746 0.79 MAPT (0.50) MEN1KMT2AMAPTCYP3A4PPARG
SCHEMBL1473746 0.77 MAPT (0.65) MEN1KMT2AMAPTCYP3A4PPARG
SCHEMBL16201607 0.76 MAPT (0.56) MEN1KMT2AMAPTCYP3A4PPARG
SCHEMBL16162246 0.75 MEN1 (0.58) MEN1KMT2AMAPTCYP3A4PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9642249-B2 Resin composition, prepreg, and substrate employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-05-02 US disclosed
US-9012572-B2 Polyphenylene ether oligomer and article employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-04-21 US disclosed
US-20140323666-A1 POLYPHENYLENE ETHER OLIGOMER AND ARTICLE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-10-30 US disclosed
US-20140322545-A1 RESIN COMPOSITION, PREPREG, AND SUBSTRATE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-10-30 US disclosed