SCHEMBL16201697

SCHEMBL16201697

CCCCCn1nc(C(=O)NC(C(N)=O)C(C)(C)C)c2ccccc21

nearest known ligand 0.94

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 14/20 0.94
CNR2 P34972 13/20 0.94
HTR3A P46098 1/20 0.46
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30609587 0.97 CNR1 (1.00) CNR1CNR2HTR3AKDM4E
SCHEMBL29275142 0.97 CNR1 (1.00) CNR1CNR2HTR3AKDM4E
SCHEMBL13691279 0.92 CNR1 (0.83) CNR1CNR2HTR3AKDM4E
SCHEMBL25366701 0.90 CNR1 (0.80) CNR1CNR2HTR3AKDM4E
SCHEMBL30353000 0.90 CNR1 (0.80) CNR1CNR2HTR3AKDM4E
SCHEMBL4054847 0.89 CNR1 (0.78) CNR1CNR2HTR3AKDM4E
SCHEMBL29275146 0.88 CNR1 (0.76) CNR1CNR2
SCHEMBL17613434 0.88 CNR1 (0.80) CNR1CNR2HTR3AKDM4E
SCHEMBL13691142 0.88 CNR1 (0.80) CNR1CNR2HTR3AKDM4E
SCHEMBL4050795 0.88 CNR1 (0.80) CNR1CNR2HTR3AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
EP-3664795-B1 CANNABIS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN AND INFLAMMATION RELATED WITH DENTAL PULP AND BONE REGENERATION RELATED TO DENTAL JAW BONE DEFECTS CANNIBITE BVBA (BE) 2024-06-19 EP claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
CN-117805259-A Method for rapidly analyzing 87 synthetic cannabinoids and metabolites thereof in urine after enzymolysis 司法鉴定科学研究院 2024-04-02 CN claimed
CN-117110457-A Analysis method for screening 50 new pollutants in sewage by micro-volume direct sample injection technology 司法鉴定科学研究院 2023-11-24 CN claimed
CN-113419018-B Pretreatment method of incense sample and method for detecting various cannabinoids in incense smoke 福州海关技术中心 2022-06-17 CN claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US disclosed
EP-4646477-A2 METHODS AND COMPOSITIONS FOR DISPLAYING PEPTIDE LIBRARIES Board of Regents, The University of Texas System (US) 2025-11-12 EP disclosed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP disclosed
US-20250241933-A1 METHODS OF TREATING SLEEP APNEA WITH A COMBINATION OF A CANNABINOID AND A CARBONIC ANHYDRASE INHIBITOR APNIMED, INC. (DELAWARE) 2025-07-31 US disclosed
EP-4543431-A1 METHODS OF TREATING SLEEP APNEA WITH A COMBINATION OF A CANNABINOID AND A CARBONIC ANHYDRASE INHIBITOR APNIMED, INC. (DELAWARE) (US) 2025-04-30 EP disclosed
CN-119403548-A Method of treating sleep apnea with a combination of cannabinoid and carbonic anhydrase inhibitors 爱普宁公司(特拉华) 2025-02-07 CN disclosed
WO-2022221613-A1 COMBINATION OF A NOREPINEPHRINE REUPTAKE INHIBITOR AND A CANNABINOID FOR USE IN TREATING SLEEP APNEA APNIMED, INC. (DELAWARE) (US) 2022-10-20 WO disclosed
CN-113419018-B Pretreatment method of incense sample and method for detecting various cannabinoids in incense smoke 福州海关技术中心 2022-06-17 CN disclosed
EP-2989452-B1 NUCLEAR MAGNETIC RESONANCE BASED SYNTHETIC INDOLE AND INDAZOLE CANNABINOID DETECTION, IDENTIFICATION, AND QUANTIFICATION HOFSTRA UNIV (US) 2021-09-29 EP disclosed
US-11085891-B2 Nuclear magnetic resonance implemented synthetic indole and indazole cannabinoid detection, identification, and quantification HOFSTRA UNIVERSITY (US) 2021-08-10 US disclosed
US-20160084779-A1 NUCLEAR MAGNETIC RESONANCE IMPLEMENTED SYNTHETIC INDOLE AND INDAZOLE CANNABINOID DETECTION, IDENTIFICATION, AND QUANTIFICATION HOFSTRA UNIVERSITY (US) 2016-03-24 US disclosed
US-20160084779-A1 NUCLEAR MAGNETIC RESONANCE IMPLEMENTED SYNTHETIC INDOLE AND INDAZOLE CANNABINOID DETECTION, IDENTIFICATION, AND QUANTIFICATION HOFSTRA UNIVERSITY (US) 2016-03-24 US disclosed
WO-2014176542-A1 NUCLEAR MAGNETIC RESONANCE IMPLEMANTED SYNTHETIC INDOLE AND INDAZOLE CANNABINOID DENTECTION, IDENTIFICATION, AND QUANTIFICATION HOFSTRA UNIVERSITY (US) 2014-10-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A CNR1 221/4885CNR2 204/4885HTR3A 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.