⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27990823 | 0.94 | — | — | |
| SCHEMBL15059632 | 0.91 | — | — | |
| SCHEMBL15059567 | 0.90 | JAK2 (0.43) | — | |
| SCHEMBL15058932 | 0.90 | — | — | |
| SCHEMBL15058905 | 0.90 | — | — | |
| SCHEMBL15059237 | 0.90 | — | — | |
| SCHEMBL15059830 | 0.89 | — | — | |
| SCHEMBL15059515 | 0.88 | EGFR (0.47) | — | |
| SCHEMBL18813576 | 0.88 | — | — | |
| SCHEMBL15058909 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794569-B1 | HETEROCYCLIC UREA COMPOUNDS | BIOTA EUROPE LTD (GB) | 2017-05-10 | — | — | EP | claimed |
| US-9060515-B2 | Heterocyclic urea compounds | BIOTA EUROPE LTD. (GB) | 2015-06-23 | — | — | US | disclosed |
| US-9060515-B2 | Heterocyclic urea compounds | BIOTA EUROPE LTD. (GB) | 2015-06-23 | — | — | US | disclosed |
| US-20140323486-A1 | HETEROCYCLIC UREA COMPOUNDS | SPERO GYRASE, INC. | 2014-10-30 | — | — | US | disclosed |
| US-20140323486-A1 | HETEROCYCLIC UREA COMPOUNDS | SPERO GYRASE, INC. | 2014-10-30 | — | — | US | disclosed |