Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13056648 | 0.98 | EPHX2 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8612225 | 0.84 | TSHR (0.43) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4149482 | 0.82 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Tetraethylene Glycol SCHEMBL4143923 | 0.82 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Pentaethylene Glycol SCHEMBL28557049 | 0.82 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4143918 | 0.82 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Triethylene Glycol SCHEMBL1627441 | 0.82 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Hexaethylene Glycol SCHEMBL4154184 | 0.82 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4140373 | 0.82 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Triethylene Glycol SCHEMBL29198607 | 0.82 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9719986-B2 | Haptens, hapten conjugates, compositions thereof preparation and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20140323336-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-10-30 | — | — | US | disclosed |