SCHEMBL16202913

SCHEMBL16202913

Cc1ccc2c(c1)c1cc3c(cc1c1cc4c5ccccc5n(-c5ccccc5)c4cc21)c1cc(C)ccc1c1cc2c(cc31)c1ccccc1n2-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.56
ATM Q13315 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
HTT P42858 3/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
MAPK8 P45983 1/20 0.37
MAPK1 P28482 2/20 0.37
PGR P06401 2/20 0.37
MAT2A P31153 1/20 0.37
RORA P35398 1/20 0.37
RORC P51449 1/20 0.37
RORB Q92753 1/20 0.37
FGFR1 P11362 1/20 0.36
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
PLA2G2A P14555 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16202915 1.00 KDM4E (0.56) KDM4EATML3MBTL1BCHEACHE
SCHEMBL24729021 0.94 KDM4E (0.64) KDM4EATML3MBTL1BCHEACHE
SCHEMBL10206166 0.92 KDM4E (0.62) KDM4EATML3MBTL1BCHEACHE
SCHEMBL1104947 0.92 KDM4E (0.62) KDM4EATML3MBTL1BCHEACHE
SCHEMBL10206146 0.90 KDM4E (0.60) KDM4EATML3MBTL1BCHEACHE
SCHEMBL10206143 0.90 KDM4E (0.60) KDM4EATML3MBTL1BCHEACHE
SCHEMBL16204727 0.89 KDM4E (0.49) KDM4EATML3MBTL1HTTLMNA
SCHEMBL18416291 0.89 KDM4E (0.52) KDM4EATML3MBTL1BCHEACHE
SCHEMBL262331 0.89 KDM4E (0.67) KDM4EATML3MBTL1BCHEACHE
SCHEMBL31373788 0.89 KDM4E (0.67) KDM4EATML3MBTL1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140319495-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY SYSTEM CANON KABUSHIKI KAISHA (JP) 2014-10-30 US disclosed
US-20140319495-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY SYSTEM CANON KABUSHIKI KAISHA (JP) 2014-10-30 US disclosed