⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26537599 | 1.00 | — | — | |
| Acetic Acid SCHEMBL31261309 | 0.81 | GRIK1 (0.59) | — | |
| SCHEMBL14227026 | 0.79 | GRIK1 (0.41) | — | |
| SCHEMBL28130572 | 0.79 | — | — | |
| SCHEMBL14227024 | 0.79 | GRIK1 (0.41) | — | |
| SCHEMBL24296090 | 0.79 | GRIK1 (0.41) | — | |
| SCHEMBL1045132 | 0.77 | — | — | |
| SCHEMBL616036 | 0.77 | — | — | |
| SCHEMBL44428 | 0.77 | — | — | |
| SCHEMBL4619445 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365556-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230242491-A1 | DIMERS FROM BIOREACHABLE MOLECULES AS COPOLYMERS | ZYMERGEN INC. (US) | 2023-08-03 | — | — | US | disclosed |
| US-11673887-B2 | N-acyl amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20140322302-A1 | THERAPEUTIC PEPTIDES | COMBIMAB, INC (US) | 2014-10-30 | — | — | US | disclosed |