Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.74 |
| ▸ | CNR1 | P21554 | 10/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | MLNR | O43193 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25235100 | 0.90 | CNR2 (0.71) | CNR2CNR1MEN1MAPTKMT2A | |
| SCHEMBL4781711 | 0.89 | CNR1 (0.73) | CNR2CNR1MAPTCYP2C9GPR55 | |
| SCHEMBL16197627 | 0.88 | CNR2 (0.69) | CNR2CNR1CYP2C9GPR55ABCC4 | |
| SCHEMBL24208719 | 0.88 | CNR2 (0.68) | CNR2CNR1CYP2C9GPR55ABCC4 | |
| SCHEMBL14247043 | 0.86 | CNR2 (0.68) | CNR2CNR1 | |
| SCHEMBL26053904 | 0.86 | CNR2 (0.66) | CNR2CNR1CYP2C9GPR55ABCC4 | |
| SCHEMBL24208718 | 0.83 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL14247021 | 0.83 | CNR1 (0.78) | CNR2CNR1 | |
| SCHEMBL17203431 | 0.82 | CNR2 (0.61) | CNR2CNR1MEN1MAPTKMT2A | |
| SCHEMBL14246986 | 0.82 | CNR1 (0.82) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174457-A1 | PYRAZOLE CARBOXYLIC ACID ANALOGUES AS ANTI-MYCOBACTERIAL DRUG CANDIDATES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-30 | — | — | WO | disclosed |