Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620738 | 1.00 | ADRB3 (0.50) | ADRB3ADRB1MKNK1MKNK2ADRB2 | |
| SCHEMBL1622696 | 0.93 | ADRB3 (0.56) | ADRB3ADRB1MKNK1MKNK2ADRB2 | |
| SCHEMBL1622692 | 0.93 | ADRB3 (0.56) | ADRB3ADRB1MKNK1MKNK2ADRB2 | |
| SCHEMBL1621062 | 0.90 | ADRB3 (0.58) | ADRB3ADRB1MKNK1MKNK2ADRB2 | |
| SCHEMBL1621064 | 0.90 | ADRB3 (0.58) | ADRB3ADRB1MKNK1MKNK2ADRB2 | |
| SCHEMBL1621056 | 0.90 | ADRB3 (0.58) | ADRB3ADRB1MKNK1MKNK2ADRB2 | |
| SCHEMBL1621053 | 0.90 | ADRB3 (0.58) | ADRB3ADRB1MKNK1MKNK2ADRB2 | |
| SCHEMBL1621952 | 0.90 | ADRB3 (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL1621949 | 0.90 | ADRB3 (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5178742 | 0.89 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928264-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2011-04-19 | — | — | US | disclosed |
| EP-1791811-B1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2009-12-23 | — | — | EP | disclosed |
| US-20080039506-A1 | Aminoalcohol Derivatives | ASTELLAS PHARMA INC. (JP) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039506-A1 | Aminoalcohol Derivatives | HRH4, HRH2, CBR3 | ADRB3 40/4885ADRB1 19/4885MKNK1 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.