Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTAP | Q13126 | 17/20 | 0.74 |
| ▸ | PNP | P00491 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22212754 | 0.85 | MTAP (1.00) | MTAPPNP | |
| SCHEMBL22212778 | 0.85 | MTAP (1.00) | MTAPPNP | |
| SCHEMBL1222218 | 0.85 | MTAP (1.00) | MTAPPNP | |
| SCHEMBL1222949 | 0.85 | MTAP (1.00) | MTAPPNP | |
| SCHEMBL1222656 | 0.85 | MTAP (1.00) | MTAPPNP | |
| SCHEMBL1223318 | 0.85 | MTAP (1.00) | MTAPPNP | |
| SCHEMBL14262851 | 0.84 | MTAP (0.72) | MTAP | |
| SCHEMBL1221895 | 0.83 | MTAP (0.84) | MTAPPNP | |
| SCHEMBL17010069 | 0.81 | MTAP (1.00) | MTAPPNP | |
| SCHEMBL22204045 | 0.81 | MTAP (1.00) | MTAPPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049543-B1 | ACYCLIC AMINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | CALLAGHAN INNOVATION RES LTD (NZ) | 2014-11-05 | — | — | EP | claimed |