SCHEMBL1620865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1621737	0.93	HRH3 (0.51)	HRH3KDRAURKAFGFR1FLT1
	SCHEMBL1623203	0.89	KDR (0.53)	HRH3KDRAURKAFGFR1FLT1
	SCHEMBL1622691	0.88	HRH3 (0.43)	HRH3KDRAURKAFGFR1FLT1
	SCHEMBL1622953	0.86	LCK (0.41)	HRH3KDRAURKAFGFR1FLT1
	SCHEMBL1622655	0.86	KDR (0.47)	HRH3KDRAURKAFGFR1FLT1
	SCHEMBL1621980	0.84	ITK (0.52)	HRH3KDRAURKAFGFR1FLT1
	SCHEMBL1622372	0.82	FGFR1 (0.69)	HRH3FGFR1FLT1HTR3A
	SCHEMBL1621132	0.82	LCK (0.50)	HRH3KDRAURKAFGFR1FLT1
	SCHEMBL1623222	0.81	ITK (0.45)	HRH3FGFR1FLT1LCKTXK
	SCHEMBL13886336	0.80	HRH3 (0.49)	HRH3KDRAURKAFGFR1FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.