Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211942 | 0.89 | CNR2 (0.71) | CNR2 | |
| SCHEMBL16212006 | 0.87 | CNR2 (0.73) | CNR2 | |
| SCHEMBL20162297 | 0.87 | CNR2 (0.73) | CNR2 | |
| SCHEMBL20162298 | 0.86 | CNR2 (0.71) | CNR2 | |
| SCHEMBL16212009 | 0.86 | CNR2 (0.71) | CNR2 | |
| SCHEMBL20162318 | 0.86 | CNR2 (0.71) | CNR2 | |
| SCHEMBL16211909 | 0.86 | CNR2 (0.71) | CNR2 | |
| SCHEMBL16211912 | 0.85 | CNR2 (0.70) | CNR2 | |
| SCHEMBL16211484 | 0.81 | CNR2 (1.00) | CNR2 | |
| SCHEMBL16211521 | 0.81 | CNR2 (1.00) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991987-A1 | PURINE DERIVATIVES AS CB2 RECEPTOR AGONISTS | F. Hoffmann-La Roche AG (CH) | 2016-03-09 | — | — | EP | claimed |
| WO-2014177490-A1 | PURINE DERIVATIVES AS CB2 RECEPTOR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-11-06 | — | — | WO | claimed |
| EP-2991987-A1 | PURINE DERIVATIVES AS CB2 RECEPTOR AGONISTS | F. Hoffmann-La Roche AG (CH) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177490-A1 | PURINE DERIVATIVES AS CB2 RECEPTOR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-11-06 | — | — | WO | disclosed |