Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | IL1RN | P18510 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29656807 | 0.88 | BIRC2 (0.64) | BIRC2CDK2KMT2ANPSR1LNPEP | |
| SCHEMBL27910970 | 0.81 | HDAC1 (0.66) | NPSR1MDM4MDM2HDAC1HDAC6 | |
| SCHEMBL2337076 | 0.81 | HDAC1 (0.66) | NPSR1MDM4MDM2HDAC1HDAC6 | |
| SCHEMBL18220518 | 0.81 | HDAC1 (0.66) | NPSR1MDM4MDM2HDAC1HDAC6 | |
| SCHEMBL14472130 | 0.81 | HDAC1 (0.66) | NPSR1MDM4MDM2HDAC1HDAC6 | |
| SCHEMBL14472192 | 0.81 | HDAC1 (0.66) | NPSR1MDM4MDM2HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL29094270 | 0.80 | ESR1 (0.52) | BIRC2CDK2CNR1CNR2KMT2A | |
| Hydrochloric Acid SCHEMBL29094271 | 0.80 | ESR1 (0.52) | BIRC2CDK2CNR1CNR2KMT2A | |
| SCHEMBL42986 | 0.79 | HDAC1 (0.64) | CNR1CNR2NPSR1LNPEPMDM4 | |
| SCHEMBL43741 | 0.79 | HDAC1 (0.64) | CNR1CNR2NPSR1LNPEPMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014177406-A1 | COMPOSITION COMPRISING AT LEAST THREE ACTIVE AGENTS FOR COLOURING AND/OR PIGMENTING KERATIN MATERIALS | L'OREAL (FR) | 2014-11-06 | — | — | WO | claimed |
| WO-2014177406-A1 | COMPOSITION COMPRISING AT LEAST THREE ACTIVE AGENTS FOR COLOURING AND/OR PIGMENTING KERATIN MATERIALS | L'OREAL (FR) | 2014-11-06 | — | — | WO | disclosed |