Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18227199 | 1.00 | TSHR (0.40) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL8200996 | 1.00 | TSHR (0.40) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL1661717 | 1.00 | TSHR (0.40) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL21118087 | 1.00 | TSHR (0.40) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL5326180 | 0.97 | — | — | |
| SCHEMBL31324014 | 0.86 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL30456060 | 0.86 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL22589673 | 0.86 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL12360400 | 0.86 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL30433623 | 0.86 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991677-A1 | SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER | Yale University (US) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014178878-A1 | SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER | YALE UNIVERSITY (US) | 2014-11-06 | — | — | WO | disclosed |