Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087558 | 0.87 | IDO1 (0.44) | HTR2AHTR2CHTR2BATMIDO1 | |
| SCHEMBL2791633 | 0.84 | TAAR1 (0.40) | HTR2AHTR2CHTR2BATMIDO1 | |
| SCHEMBL6814904 | 0.82 | HTR2A (0.46) | HTR2AHTR2CHTR2BATMIDO1 | |
| SCHEMBL26464609 | 0.81 | IDO1 (0.39) | HTR2AHTR2CHTR2BATMIDO1 | |
| SCHEMBL806196 | 0.78 | TAAR1 (0.56) | HTR2AIDO1TSHRMAPK1TAAR1 | |
| SCHEMBL2793814 | 0.78 | TAAR1 (0.43) | HTR2AHTR2CHTR2BATMIDO1 | |
| SCHEMBL2797336 | 0.78 | IDO1 (0.37) | HTR2AHTR2CHTR2BATMIDO1 | |
| SCHEMBL4645916 | 0.77 | HTR2A (0.62) | HTR2AHTR2CHTR2BIDO1TSHR | |
| Hydrochloric Acid SCHEMBL23577777 | 0.77 | TAAR1 (0.55) | HTR2AIDO1TSHRMAPK1TAAR1 | |
| SCHEMBL12398665 | 0.77 | IDO1 (0.41) | ATMIDO1KMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480531-B1 | PYRROLIDINONE CARBOXAMIDE DERIVATIVES AS CHEMERIN-R (CHEMR23) MODULATORS | CHEMOCENTRYX INC (US) | 2014-11-05 | — | — | EP | disclosed |