Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 19/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | YES1 | P07947 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | FGR | P09769 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.52 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.52 |
| ▸ | PAK5 | Q9P286 | 1/20 | 0.52 |
| ▸ | FER | P16591 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14908726 | 1.00 | SYK (0.63) | SYKKCNH2JAK2LCKYES1 | |
| SCHEMBL14928924 | 1.00 | SYK (0.63) | SYKKCNH2JAK2LCKYES1 | |
| SCHEMBL14908694 | 1.00 | SYK (0.63) | SYKKCNH2JAK2LCKYES1 | |
| SCHEMBL14909499 | 0.91 | SYK (0.64) | SYKKCNH2JAK2LCKYES1 | |
| SCHEMBL16171096 | 0.90 | SYK (0.51) | SYKKCNH2JAK2LCKYES1 | |
| SCHEMBL16164284 | 0.90 | SYK (0.51) | SYKKCNH2JAK2LCKYES1 | |
| SCHEMBL16169449 | 0.90 | SYK (0.51) | SYKKCNH2JAK2LCKYES1 | |
| SCHEMBL16171054 | 0.90 | SYK (0.51) | SYKKCNH2JAK2LCKYES1 | |
| SCHEMBL16169440 | 0.90 | SYK (0.51) | SYKKCNH2JAK2LCKYES1 | |
| SCHEMBL16164956 | 0.90 | SYK (0.51) | SYKKCNH2JAK2LCKYES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799431-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2014-11-05 | — | — | EP | disclosed |