⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469714 | 0.73 | — | — | |
| SCHEMBL14923040 | 0.71 | — | — | |
| SCHEMBL2803526 | 0.63 | — | — | |
| SCHEMBL23692087 | 0.62 | — | — | |
| SCHEMBL23957391 | 0.60 | — | — | |
| SCHEMBL3793814 | 0.60 | — | — | |
| SCHEMBL3883600 | 0.58 | — | — | |
| SCHEMBL21307460 | 0.56 | — | — | |
| SCHEMBL7193444 | 0.56 | — | — | |
| SCHEMBL10305771 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040658-B2 | Thiol-selective water-soluble polymer derivatives | NEKTAR THERAPEUTICS (US) | 2015-05-26 | — | — | US | disclosed |
| US-20140330041-A1 | THIOL-SELECTIVE WATER-SOLUBLE POLYMER DERIVATIVES | NEKTAR THERAPEUTICS (US) | 2014-11-06 | — | — | US | disclosed |