Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 16/20 | 0.66 |
| ▸ | ERBB4 | Q15303 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16219896 | 0.92 | EGFR (0.75) | EGFRERBB2ERBB4 | |
| SCHEMBL16219921 | 0.92 | EGFR (0.80) | EGFRERBB2ERBB4 | |
| SCHEMBL16219780 | 0.90 | EGFR (0.68) | EGFRERBB2ERBB4 | |
| SCHEMBL16219781 | 0.90 | EGFR (0.68) | EGFRERBB2ERBB4 | |
| SCHEMBL18595815 | 0.90 | EGFR (0.70) | EGFRERBB2ERBB4 | |
| SCHEMBL16219937 | 0.89 | EGFR (0.73) | EGFRERBB2ERBB4 | |
| SCHEMBL16219936 | 0.89 | EGFR (0.79) | EGFRERBB2ERBB4 | |
| SCHEMBL16219922 | 0.88 | EGFR (0.73) | EGFRERBB2ERBB4 | |
| SCHEMBL16219886 | 0.88 | EGFR (0.77) | EGFRERBB2ERBB4 | |
| SCHEMBL15771870 | 0.88 | EGFR (0.72) | EGFRERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014177038-A1 | AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-11-06 | — | — | WO | disclosed |