SCHEMBL1622344

SCHEMBL1622344

CCCCCS(=O)(=O)NC(=O)c1ccc(-c2ccc(CCN(C[C@H](O)c3ccccc3)C(=O)OC(C)(C)C)cc2)cc1OC(C)C

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 20/20 0.52
ADRB1 P08588 11/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4395985 0.91 ADRB3 (0.56) ADRB3ADRB1
SCHEMBL4395986 0.91 ADRB3 (0.56) ADRB3ADRB1
SCHEMBL5704050 0.90 ADRB3 (0.55) ADRB3ADRB1
SCHEMBL1620389 0.89 ADRB3 (0.66) ADRB3ADRB1
SCHEMBL5703865 0.89 ADRB3 (0.56) ADRB3ADRB1
SCHEMBL5703705 0.88 ADRB3 (0.56) ADRB3ADRB1
SCHEMBL1622619 0.87 ADRB3 (0.49) ADRB3ADRB1
SCHEMBL5704120 0.87 ADRB3 (0.65) ADRB3ADRB1
SCHEMBL4584336 0.86 ADRB3 (0.59) ADRB3ADRB1
SCHEMBL4584331 0.86 ADRB3 (0.59) ADRB3ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7928264-B2 Aminoalcohol derivatives ASTELLAS PHARMA INC. (JP) 2011-04-19 US disclosed
EP-1697301-A2 AMINOALCOHOL DERIVATIVES Astellas Pharma Inc. (JP) 2006-09-06 EP disclosed
WO-2005061433-A2 AMINOALCOHOL DERIVATIVES ASTELLAS PHARMA INC. (JP) 2005-07-07 WO disclosed