Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.67 |
| ▸ | ITGA5 | P08648 | 20/20 | 0.67 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.67 |
| ▸ | ITGAV | P06756 | 12/20 | 0.67 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16223661 | 0.93 | ITGB1 (0.69) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL16223806 | 0.93 | ITGB1 (0.73) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL16223676 | 0.92 | ITGB1 (0.67) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL16223847 | 0.91 | ITGB1 (0.81) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL16223675 | 0.90 | ITGB1 (0.82) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5561020 | 0.90 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL14453425 | 0.90 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL16223671 | 0.89 | ITGB1 (0.75) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL16223828 | 0.88 | ITGB1 (0.69) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL16223834 | 0.88 | ITGB1 (0.72) | ITGB1ITGA5ITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727811-B1 | NEW COMPOUNDS FOR THE INHIBITION OF ANGIOGENESIS AND USE OF THEREOF | SHIRE ORPHAN THERAPIES GMBH (DE) | 2014-11-12 | — | — | EP | claimed |