Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17555401 | 0.85 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16224842 | 0.85 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL20560434 | 0.82 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16224846 | 0.82 | MAPK1 (1.00) | MAPK1 | |
| Trifluoroacetic Acid SCHEMBL16213585 | 0.80 | MAPK1 (0.89) | MAPK1 | |
| Trifluoroacetic Acid SCHEMBL16213581 | 0.80 | MAPK1 (0.89) | MAPK1 | |
| SCHEMBL17555411 | 0.79 | MAPK1 (0.69) | MAPK1USP1 | |
| SCHEMBL16224849 | 0.79 | MAPK1 (0.69) | MAPK1USP1 | |
| SCHEMBL22382060 | 0.73 | MAPK1 (1.00) | MAPK1 | |
| Trifluoroacetic Acid SCHEMBL16213533 | 0.72 | MAPK1 (0.66) | MAPK1USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014179154-A2 | NOVEL COMPOUNDS THAT ARE ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-11-06 | — | — | WO | disclosed |