Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.75 |
| ▸ | ITGA5 | P08648 | 20/20 | 0.75 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.75 |
| ▸ | ITGAV | P06756 | 14/20 | 0.75 |
| ▸ | ITGB5 | P18084 | 9/20 | 0.74 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14453425 | 0.95 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5561020 | 0.95 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5561284 | 0.88 | ITGB1 (0.85) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL14453421 | 0.88 | ITGB1 (0.85) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL14453417 | 0.87 | ITGB1 (0.90) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5561134 | 0.87 | ITGB1 (0.90) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL14453424 | 0.87 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5560765 | 0.87 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5560796 | 0.86 | ITGB1 (1.00) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL14453396 | 0.86 | ITGB1 (1.00) | ITGB1ITGA5ITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727811-B1 | NEW COMPOUNDS FOR THE INHIBITION OF ANGIOGENESIS AND USE OF THEREOF | SHIRE ORPHAN THERAPIES GMBH (DE) | 2014-11-12 | — | — | EP | disclosed |