Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10130167 | 0.83 | SCN9A (0.41) | SCN9ACDC7 | |
| SCHEMBL10129962 | 0.76 | SCN9A (0.40) | SCN9A | |
| SCHEMBL14891244 | 0.73 | SCN9A (0.47) | SCN9A | |
| SCHEMBL14891248 | 0.69 | SCN9A (0.40) | SCN9ACYP1A2CYP3A4ALOX15TSHR | |
| SCHEMBL20256920 | 0.69 | GAA (0.35) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL10147882 | 0.69 | SCN9A (0.53) | SCN9A | |
| SCHEMBL10130230 | 0.67 | SCN9A (0.57) | SCN9A | |
| SCHEMBL21524340 | 0.65 | CYP1A2 (0.36) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL19001212 | 0.65 | MEN1 (0.35) | CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL10129756 | 0.65 | SCN9A (0.47) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590957-B1 | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | PFIZER LTD (GB) | 2014-11-12 | — | — | EP | disclosed |