Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17912 | 0.91 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL26736145 | 0.88 | SMN1; SMN2 (0.62) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL28959621 | 0.88 | NR1I2 (0.46) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL19978962 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL7261016 | 0.85 | CYP3A4 (0.55) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL15037994 | 0.85 | SMN1; SMN2 (0.58) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL18614940 | 0.85 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL22091891 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| 1,3-Propanediol SCHEMBL17704098 | 0.84 | SMN1; SMN2 (0.62) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL16004370 | 0.83 | AR (0.58) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335080-A1 | ESTER DERIVATIVES OF ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-11-13 | — | — | US | disclosed |
| US-20140335080-A1 | ESTER DERIVATIVES OF ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335080-A1 | ESTER DERIVATIVES OF ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | AR, ESRRA, KLK3 | KDM4E 923/4885ALDH1A1 1270/4885SMN1; SMN2 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.