SCHEMBL16236084

SCHEMBL16236084

CC(C)(C)C(=O)Oc1ccc2ccccc2c1-c1c(OC(=O)c2ccccc2)ccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 10/20 0.49
▸ MAPT P10636 5/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ JAK2 O60674 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ ESR1 P03372 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ ESR2 Q92731 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16237325 0.90 MAPT (0.53) ELANEMAPTHSD17B10
SCHEMBL16236952 0.89 MAPT (0.57) MAPTKMT2ATDP1MEN1SMN1; SMN2
SCHEMBL16236423 0.85 MAPT (0.65) ELANEMAPTKMT2AMEN1L3MBTL1
SCHEMBL16236807 0.85 MAPT (0.47) ELANEMAPTGAANPSR1
SCHEMBL16236334 0.85 MAPT (0.50) ELANEMAPTKMT2ATDP1MEN1
SCHEMBL16236873 0.85 MAPT (0.65) MAPTKMT2ATDP1MEN1L3MBTL1
SCHEMBL417088 0.83 MAPT (0.48) ELANEMAPTKMT2AMEN1
Hydrochloric Acid SCHEMBL16236126 0.82 MAPT (0.49) ELANEMAPTHSD17B10
SCHEMBL16236576 0.82 KMT2A (0.54) MAPTKMT2ATDP1MEN1SMN1; SMN2
SCHEMBL15548022 0.81 ELANE (0.66) ELANEMAPTKMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2997050-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2018-01-17 — — EP disclosed
US-9714303-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2017-07-25 — — US disclosed
US-20160115261-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2016-04-28 — — US disclosed
EP-2997050-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2016-03-23 — — EP disclosed
WO-2014184171-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-11-20 — — WO disclosed
EP-2803678-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2014-11-19 — — EP disclosed
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