Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.54 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.52 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.52 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.52 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239240 | 0.94 | KDM4E (0.69) | KDM4EMEN1RECQLKMT2APTGS2 | |
| SCHEMBL15548053 | 0.92 | KDM4E (0.67) | KDM4EMEN1RECQLKMT2APTGS2 | |
| SCHEMBL16237167 | 0.88 | MEN1 (0.61) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL14315096 | 0.87 | POLM (0.66) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL9312879 | 0.86 | KMT2A (0.60) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL16236583 | 0.86 | KDM4E (0.60) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL15547873 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APTGS2 | |
| SCHEMBL12863966 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APTGS2 | |
| SCHEMBL15548540 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APTGS2 | |
| SCHEMBL15547553 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997050-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2018-01-17 | — | — | EP | disclosed |
| US-9714303-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2017-07-25 | — | — | US | disclosed |
| US-20160115261-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2016-04-28 | — | — | US | disclosed |
| EP-2997050-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184171-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-11-20 | — | — | WO | disclosed |
| EP-2803678-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2014-11-19 | — | — | EP | disclosed |