Phenol

Phenol

SCHEMBL16237371

F.F.F.F.F.Oc1ccccc1

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.92
CA2 P00918 4/20 0.92
CA14 Q9ULX7 4/20 0.92
CA9 Q16790 3/20 0.92
CA3 P07451 3/20 0.92
CA4 P22748 3/20 0.92
CA1 P00915 2/20 0.92
TDP1 Q9NUW8 2/20 0.92
GLA P06280 1/20 0.92
MMP3 P08254 1/20 0.59
BCL2L1 Q07817 1/20 0.59
ALDH1A1 P00352 4/20 0.54
CYP3A4 P08684 4/20 0.54
NPC1 O15118 3/20 0.54
LMNA P02545 3/20 0.54
CA5A P35218 3/20 0.54
HSD17B10 Q99714 3/20 0.54
CA5B Q9Y2D0 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL1513522 1.00 CA12 (0.92) CA12CA2CA14CA9CA3
Phenol SCHEMBL3874721 1.00
Phenol SCHEMBL28805625 1.00 CA12 (0.92) CA12CA2CA14CA9CA3
Phenol SCHEMBL28223048 1.00 CA12 (0.92) CA12CA2CA14CA9CA3
Phenol SCHEMBL1780285 1.00 CA12 (0.92) CA12CA2CA14CA9CA3
Phenol SCHEMBL1513520 1.00 CA12 (0.92) CA12CA2CA14CA9CA3
Phenol SCHEMBL14954090 0.96 CA12 (0.85) CA12CA2CA14CA9CA3
Phenol SCHEMBL14953991 0.96 CA12 (0.85) CA12CA2CA14CA9CA3
Phenol SCHEMBL19328641 0.96 CA12 (0.85) CA12CA2CA14CA9CA3
Phenol SCHEMBL2461182 0.96 CA12 (0.85) CA12CA2CA14CA9CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105585547-A 4-sulfur pentafluoride phenol compound, preparing method and preparing method for sulfur pentafluoride substituted benzopyran compound GUANGZHOU INST BIOMED & HEALTH 2016-05-18 CN claimed
US-10414744-B2 4-sulfur pentafluoride phenol compound and preparation method therefor, and preparation method for sulfur pentafluoride substituted benzopyran compound Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences (CN) 2019-09-17 US disclosed
US-20190084957-A1 4-SULFUR PENTAFLUORIDE PHENOL COMPOUND AND PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR SULFUR PENTAFLUORIDE SUBSTITUTED BENZOPYRAN COMPOUND Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences (CN) 2019-03-21 US disclosed
EP-3428154-A1 4-SULFUR PENTAFLUORIDE PHENOL COMPOUND AND PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR SULFUR PENTAFLUORIDE SUBSTITUTED BENZOPYRAN COMPOUND Guangzhou Institutes Of Biomedicine And Health Chinese Academy Of Sciences (CN) 2019-01-16 EP disclosed
US-20160221992-A1 DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2016-08-04 US disclosed
CN-105585547-A 4-sulfur pentafluoride phenol compound, preparing method and preparing method for sulfur pentafluoride substituted benzopyran compound GUANGZHOU INST BIOMED & HEALTH 2016-05-18 CN disclosed
EP-2996726-A1 DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF Université de Strasbourg (FR) 2016-03-23 EP disclosed
WO-2014184503-A1 DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF UNIVERSITE DE STRASBOURG (FR) 2014-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160221992-A1 DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF MSR1, CD74, CD4 CA12 1330/4885CA2 1113/4885CA14 1463/4885
US-20190084957-A1 4-SULFUR PENTAFLUORIDE PHENOL COMPOUND AND PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR SULFUR PENTAFLUORIDE SUBSTITUTED BENZOPYRAN COMPOUND SALL4, FGFR4, CYP4F11 CA12 3120/4885CA2 4043/4885CA14 1622/4885
US-10414744-B2 4-sulfur pentafluoride phenol compound and preparation method therefor, and preparation method for sulfur pentafluoride substituted benzopyran compound SALL4, FGFR4, CYP4F11 CA12 3120/4885CA2 4043/4885CA14 1622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.