Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16236938 | 0.99 | KMT2A (0.44) | KMT2AMAPTESR1ESR2SMN1; SMN2 | |
| SCHEMBL16239266 | 0.94 | KMT2A (0.46) | KMT2AMAPTESR1ESR2SMN1; SMN2 | |
| SCHEMBL16237015 | 0.93 | KMT2A (0.47) | KMT2AMAPTESR1ESR2SMN1; SMN2 | |
| SCHEMBL22090204 | 0.80 | MAPT (0.39) | KMT2AMAPTSMN1; SMN2LMNASLC6A3 | |
| SCHEMBL30620531 | 0.76 | KMT2A (0.49) | KMT2AMAPTESR1ESR2SMN1; SMN2 | |
| SCHEMBL20088757 | 0.76 | ESR1 (0.41) | KMT2AMAPTESR1ESR2SMN1; SMN2 | |
| SCHEMBL20088755 | 0.76 | ESR1 (0.41) | KMT2AMAPTESR1ESR2SMN1; SMN2 | |
| SCHEMBL20088762 | 0.76 | ESR1 (0.41) | KMT2AMAPTESR1ESR2SMN1; SMN2 | |
| SCHEMBL16239399 | 0.73 | BCL2L1 (0.52) | KMT2AMEN1BCL2L1BADACACB | |
| SCHEMBL1284960 | 0.73 | BCL2L1 (0.58) | KMT2AMAPTMEN1GAABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997050-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2018-01-17 | — | — | EP | disclosed |
| EP-2803678-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2014-11-19 | — | — | EP | disclosed |