Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239722 | 0.94 | SCN9A (0.63) | SCN9ASCN5A | |
| SCHEMBL365795 | 0.93 | SCN9A (0.58) | SCN9ASCN5AMRGPRX4 | |
| SCHEMBL10202046 | 0.90 | SCN9A (0.70) | SCN9ASCN5A | |
| SCHEMBL16240129 | 0.88 | SCN9A (0.63) | SCN9ASCN5A | |
| SCHEMBL16239898 | 0.86 | SCN9A (0.60) | SCN9ASCN5A | |
| SCHEMBL16240251 | 0.85 | SCN9A (0.59) | SCN9ASCN5A | |
| SCHEMBL16239671 | 0.85 | SCN9A (0.61) | SCN9ASCN5A | |
| SCHEMBL16239824 | 0.84 | SCN9A (0.58) | SCN9ASCN5AMRGPRX4 | |
| SCHEMBL14890273 | 0.84 | SCN9A (0.60) | SCN9ASCN5A | |
| SCHEMBL364497 | 0.83 | SCN9A (0.57) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593428-B1 | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | PFIZER LTD (GB) | 2014-11-19 | — | — | EP | disclosed |