Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239848 | 0.87 | TACR3 (0.71) | TACR3RORC | |
| SCHEMBL16239673 | 0.84 | TACR3 (0.73) | TACR3RORC | |
| SCHEMBL16239922 | 0.84 | TACR3 (0.73) | TACR3RORC | |
| SCHEMBL10277231 | 0.83 | TACR3 (1.00) | TACR3 | |
| SCHEMBL16239792 | 0.83 | TACR3 (0.73) | TACR3RORC | |
| SCHEMBL16239483 | 0.82 | TACR3 (0.74) | TACR3 | |
| SCHEMBL16239850 | 0.81 | TACR3 (0.75) | TACR3RORC | |
| SCHEMBL16239884 | 0.80 | TACR3 (0.75) | TACR3 | |
| SCHEMBL16239485 | 0.79 | TACR3 (0.80) | TACR3 | |
| SCHEMBL16239566 | 0.78 | TACR3 (0.77) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661432-B1 | PYRROLIDINE DERIVATIVES AS NK3 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | claimed |