Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277547 | 1.00 | TACR3 (1.00) | TACR3 | |
| SCHEMBL10277541 | 0.91 | TACR3 (1.00) | TACR3 | |
| SCHEMBL10277234 | 0.90 | TACR3 (1.00) | TACR3 | |
| SCHEMBL16239682 | 0.86 | TACR3 (0.75) | TACR3 | |
| SCHEMBL12500538 | 0.85 | TACR3 (1.00) | TACR3 | |
| SCHEMBL10277309 | 0.85 | TACR3 (1.00) | TACR3 | |
| SCHEMBL10277226 | 0.84 | TACR3 (1.00) | TACR3 | |
| SCHEMBL10277404 | 0.84 | TACR3 (1.00) | TACR3 | |
| SCHEMBL10277565 | 0.84 | TACR3 (1.00) | TACR3 | |
| SCHEMBL10277440 | 0.84 | TACR3 (1.00) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661432-B1 | PYRROLIDINE DERIVATIVES AS NK3 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | claimed |