Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 18/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.51 |
| ▸ | SRC | P12931 | 3/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | MTOR | P42345 | 2/20 | 0.51 |
| ▸ | PRKDC | P78527 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HCK | P08631 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955596 | 0.90 | PIK3CG (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBSRC | |
| SCHEMBL29479406 | 0.90 | PIK3CG (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBSRC | |
| SCHEMBL16241639 | 0.89 | PIK3CD (0.68) | PIK3CGPIK3CDPIK3CAPIK3CBSRC | |
| SCHEMBL20045139 | 0.89 | PIK3CG (0.62) | PIK3CGPIK3CDPIK3CAPIK3CBSRC | |
| SCHEMBL18708940 | 0.86 | PIK3CG (0.57) | PIK3CGPIK3CDPIK3CAPIK3CBSRC | |
| SCHEMBL9884109 | 0.84 | PIK3CD (0.72) | PIK3CGPIK3CDPIK3CAPIK3CBSRC | |
| SCHEMBL9884211 | 0.83 | PIK3CD (0.71) | PIK3CGPIK3CDPIK3CAPIK3CBSRC | |
| SCHEMBL9899453 | 0.83 | PIK3CG (0.55) | PIK3CGPIK3CDPIK3CAPIK3CBSRC | |
| SCHEMBL9924632 | 0.82 | PIK3CG (0.69) | PIK3CGPIK3CDPIK3CAPIK3CBSRC | |
| SCHEMBL9924613 | 0.82 | PIK3CG (0.76) | PIK3CGPIK3CDPIK3CAPIK3CBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216982-B2 | Certain chemical entities, compositions and methods | INTELLIKINE LLC (US) | 2015-12-22 | — | — | US | disclosed |
| US-20140341894-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140341894-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | PIK3CA, AKT3, PIK3C2A | PIK3CG 8/4885PIK3CD 7/4885PIK3CA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.